Total Synthesis of Marine Cyclic Guanidine Compounds and Development of Novel Guanidine Type Asymmetric Organocatalysts
نویسندگان
چکیده
منابع مشابه
[Total synthesis of marine cyclic guanidine compounds and development of novel guanidine type asymmetric organocatalysts].
Crambescidins and batzelladines, novel marine guanidine alkaloids, have unique pentacyclic and tricyclic guanidine core structures, respectively. They display a considerable array of biological activity and not surprisingly have attracted considerable synthetic interest. The first total synthesis of crambescidin 359 (7) and stereoselective total synthesis of batzelladine D (11) were accomplishe...
متن کاملA Fast Route for the Synthesis of Cyclic Guanidine Derivatives
A simple synthesis of cyclic guanidine derivatives is presented in this study. The construction of the central basic scaffolds is achieved by the application of microwave-assisted chemistry. This process completed without use of any extra reagent or protecting group manipulations. The formation of products of substituted guanidine was controlled by the temperature.
متن کاملPolycyclic Guanidine Alkaloids from Poecilosclerida Marine Sponges
Sessile marine sponges provide an abundance of unique and diversified scaffolds. In particular, marine guanidine alkaloids display a very wide range of biological applications. A large number of cyclic guanidine alkaloids, including crambines, crambescins, crambescidins, batzelladines or netamins have been isolated from Poecilosclerida marine sponges. In this review, we will explore the chemodi...
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در این پروژه ترکیبات 3-آریل-2h-بنزو[b]-4،1-اکسازین ها از مواد اولیه تجاری مشتقات دو آمینو فنول و ?-هالو کتون های آروماتیک در مایع یونی 1-اکتیل-3-متیل ایمیدازولیوم تترا فلورو بورات([omim]bf4) سنتز شده است. این واکنش توسط باز پتاسیم کربنات محلول از طریق o-آلکیلاسیون و سپس یک واکنش آمیداسیون درون مولکولی خود بخود در مدت زمان کوتاه انجام می شود. ترکیبات 4،1-بنزوکسازین به این روش با بهره خوب تا آلی ...
15 صفحه اولcomparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.
heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 2003
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi.123.387